Detection of Multidrug Resistance Uropathogenic Escherichia coli in Pregnant Women in Mosul City
DOI:
https://doi.org/10.32792/jmed.2025.29.7Keywords:
Escherichia coli, pregnant women, ESBL, CTX-M geneAbstract
One of the main bacterial infections for pregnant women is urinary tractinfection (UTI). UTIs during pregnancy are made easier by the
physiological and anatomical changes. Bacteria that produce extended
spectrum beta-lactamases (ESBLs) have proliferated globally in recent
decades. As the primary ESBL-producing bacteria, Escherichia coli are
highly valued as one of the most significant causal agents of nosocomial
infections worldwide.The purpose of the study was genotypic and
phenotyping detection of ESBL Producing Escherichia coli and its
prevalence in pregnant women.All urine samples cultured and diagnosed
by biochemical test. The positive culture for E.coli streaked on Muller
Hinton media for antibiotic susceptibility. Then MDR species were used
to assess the presence of ESBL by phentyping and genotyping
methods.The antibiotics sensitivity results are 27 (77.1 %) sensitive to
CIP and C 25 (71.4 %). resistance to CRO 8 (22.8 %), CTX 10 (28.5 %),
AMC 23 (65.7 %). The genotyping showed that from 14 isolates of
ESBL, 8 (57.14 %) were positive for CTX-M gene. The most frequent
cause of UTIs is E. coli, and the creation of ESBL makes treatment plans
more difficult and increases resistance to standard antibiotics.
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