Risk Factors For First Attack Of Febrile Convulsion: Case Control Study

Authors

  • Aida Abdul Kareem Manthar C. A. B. P. Assistant professor Department of pediatrics College of Medicine University of Basrah
  • Ahmed Mohsin Aziz M. B. Ch. B. , C. A. B. P., F.I.C.M.S .pediatric specialist in Thi-qar / Muhammed Al mosewy hospital for pediatric medicine.

Abstract

Background: Febrile seizures are the most common cause of convulsions in children. Most are simple in nature, although those with focal type , prolonged duration  more than (15 min) or those that recur within 24 hours or within the same febrile illness are considered complex. Objective: This is case- control study was carried out to :-Analyze the risk factors associated with first febrile convulsion in comparison to control group of the same age.Analyze the risk factors associated with complex febrile comvulsions.  Subjects and Methods: Patients: A case –control  study had been done at Basrah   peadiatric teaching  hospital  in pediatric medical department on 115 patients  admitted with first attack of  convulsion  and fever,their ages ranged from six months to six years.They had been admitted during  the  time from January2015 to the end of August 2015. Sixty - nine were males and 46 were females.Cases were  matched with control group of 130 children without fever or fit  in relation to age  (6 months -6 years). Results: The significant risk factors were positive family history of febrile convulsion P-value < 0.001, positive family history of developmental delay P-value < 0.01& patient s, history of  preterm gestational age P-value < 0.01.  Other risk factors were not found to be significantly correlated  with first febrile convulsion .The study has revealed  that there is a significant correlation between first complex  febrile convulsion and young age of patients (≤15 months), P-value < 0.05. The common infections  leading to febrile convulsions were  upper respiratory  infections (40 % of  the all causes) , which was  significantly associated with simple febrile convulsions. Conclusoin: From this study three risk factors for first attack febrile seizure were identified ,which may  help in  the prevention include   positive history of febrile seizures in the family  and developmental delay  and history of the prematurity .Complex type was found in 49.6 % of patients with febrile seizure and was related to young age ( ≤ 15 months) .Upper respiratory tract infections were  the most common factor related  to increase temperture in children with febrile convulsion & related to the simple type of febrile convulsions.  

References

-Michael V.Johnston.Seizures in childhood.In : Robert M.Kliegman: Nelson Textbook of Pediatrics. 19th edition, Philadelphia. WB Saunders Co 2011: 2457-2458.

-Sunil K . Febrile seizures: A review for family physicians.Indian Journal of Medical Sciences 2010 ;84(3): 161-172.

-Mohammed M, John P. Febrile seizures update and controversies. Neurosciences 2012; 20 (4): 235-242.

-Annapurna P,Paul E.Seizures.In :Lisa B,Vincent W:Comprehensive Pediatric Hospital Medicine . Philadelphia Pennsylvania.2009: 797 -799.

- Suad Al-Ossaimi, Naheda H .Recent Advances in Febrile Seizures. The Kuwait Medical Journal 2012, 56 (1): 7-12.

- Colin F,Richard N,Tim M.Neurology.In :Neil M,Peter J,Rosalind L,et al:Forfar &Arneil,s TEXTBOOK of PEDIATRICS.7th edition , Churchill Livingstone Elsevier Co 2013:860-861.

- Carol C,Peter C,Renee S,Febrile seizures.ILAE International League Against Epilepsy.2012January 59(4) 780 -783.

- Waruiru C, Appleton R. Febrile seizures: an update. Arch Dis Child 2013;89:751–756.

- Tahir S. Febrile convulsion in children: Relationship of family history to type of convulsions and age at presentation .Pakistan Paediatric Journal .2009 oct;30(6):26-8.

- Talebian A,Honarpisheh A.Risk Factors of First Febrile Seizure. MJIRC 2014;15(7):56-58.

- Wadhwa N,Bharucha B,Chablania A.An epidemiolo gic study of febrile seizure with special reference to family history and HLA.India pediatric2009 Dec; 34 (14):1479-85.

- Tonia J, Steven J. Childhood Febrile Seizures: Overview and Implications.International journal of medical sciences. 2011April 7; 21(1): 110–114.

- Ling G,Jalan R. Clinical Characteristics and Risk Factors for a Complex First Febrile Convulsion. Singapore Med Journals 2010Vol 63(8) : 264-267.

-Mohammad R,Holden k,Butler I. A Practical Approach to the Causes and Management of Febrile Seizures . J Child Neurol 2014;23:1484 -1488.

- Sadao S,Kyoka S,Masaru I .Clinical characteristics of febrile convulsion during primary HHV-6 infection.Archives of Disease in Childhood 2012;82:62-66.

- Murat T,Ayse A,Asuman Y.Prevalence and risk factors of Febrile Convulsion In Between the Ages of 3months-6Years Children in Trabzon.World congress on public health2009April 28.

- Van D ,Geerts A,Meulstee J.Reliability of the diagnosis of a first seizure.Neurology 2009;39:267-71.

- Anne T, Shlomo S , Eugene D . Risk Factors for a First Febrile Seizure: A Matched Case-Control Study.Wily InterScience : JOURNALS:Epilepsia.2013Aug;56(4):334-341.

- Eila A, Marjo k.Laila L.Increased number of febrile seizures in children born very preterm :Relation of neonatal,febrile and epileptic seizures and neurological dysfunctioin to seizure outcome at 16 years of age.Science Direct 2012;34(8):590 -597.

-Shinnar S , Nordli D.R, Dell C.O et al.Phenomology of prolonged febrile seizure .Neurology 2009;71:170-176.

Downloads

Published

2020-09-07

Issue

Section

Articles