Evaluation Of Serum 1,5 - Anhydroglucitol Levels among Type 2 Diabetic Patients in Basrah
Keywords:Diabetes mellitus, 1,5-AG level, glycaemic control
AbstractObjective: To determine serum 1,5- anhydroglucitol (1,5-AG) levels among patients with type 2 diabetes (T2D) in Basrah, and to evaluate the changes in 1,5-AG levels with regard to the status of glycaemic control. Methods: The present study included 76 patients with T2D, 33 males and 43 females, 30-78 years of age. Height, weight, waist circumference , systolic blood pressure, and diastolic blood pressure were measured. Fasting blood glucose (FBG), glycated haemoglobin (HbA1c) and serum 1,5-AG levels were determined. Results: The study revealed that T2D patients have low serum 1,5-AG concentrations (3.62 ±1.56) µg/ml. The comparative male and female values were (3.69±1.55) µg/ml and (3.57±1.58) µg/ml. The vast majority of the included diabetic patients (90.8%) were in a state of poor glycemic control, with 6.6% have an sub-optimal metabolic control. On the other hand, good glycemic was documented in 2.6 % of patients. There were no significant differences in plasma 1,5-AG concentrations with regard to the status of glycaemic control (P > 0.05). Conclusion: T2D patients have reduced serum 1,5-AG concentrations. Thus, it could be, potentially, valuable test for the diagnosis of diabetes mellitus. Diabetic patients were in poor glycaemic state. Therefore, they are at a substantial risk for the development of diverse diabetic complications.
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