Age Distribution of Breast Mass and Validity of Used Measures in Its Diagnosis at Breast Disease Clinic in Thi-Qar 2018
Keywords:
Breast mass, validity of breast diagnostic measuresAbstract
Objective: of this study to study the effect of age and specific age groups in the distribution of breast mass in Thi-Qar, to determine the effect of most determinant factors included in obstetric history on that distribution, and to assess the validity of radiological investigations and FNA about histopathological diagnosis of breast masses for patients counseling breast disease clinic in Thi-Qar 2018. Design: A cross sectional analytical design was used. Patients: All women presented with breast mass at defined age, were included. Results: The rate of malignancy increased with age; at ages >45 years about half of cases were malignant (47%), and constitute(57.4%) of the total malignancies, while the other ages categories of < 45 years, the proportion of malignancy among cases of the same categories about (16%), and constitute (25%), (17%) for ages interval (30-45), (<30) respectively On other hand FNA are 82% specific and 96% sensitive compared to definitive histopathologic results in the diagnosis of breast masses. Conclusion The findings of the current work suggested that age was a strongly correlated factor and about 57.5% of the malignancies were above 45. FNA are 82% specific and 96% sensitive in relation to definitive histopathologic results.References
-Tabar, L.; Duffy, S.W.; Vitak, B.; Chen, H.H. and Prevost, T.C. ( 1999). The natural history of breast carcinoma: what have we learned from screening. J. cancer. 86:449–62
- Karim, S. A. M.; Ghalib, H.H.A.; Mohammed, S.A. and Fattah H. R. F. (2015). The incidence, age at diagnosis of breast cancer in the Iraqi Kurdish population and comparison to some other countries of Middle-East and West Intern. International Journal of Surgery. 13: 71-75.
American Cancer Society. Cancer Facts and Figures 2018. (https://www.cancer.org/cancer/breast-cancer/non-cancerous-breast-conditions.html ).
Majid, R.A.; Hassan, H.A.; Muhealdeen, D.A.; Mohammed, H.; and Hughson, D.(2017). Breast cancer in Iraq is associated with a unimodally distributed predominance of luminal type B over luminal type A surrogates from young to old age . BMC Women's Health. 17(1)27
Alwan, N.A.S. (2016). Breast Cancer Among Iraqi Women: Preliminary Findings From a Regional Comparative Breast Cancer Research Project. J of Glob. Oncol. 2(5): 255-258.
American Cancer Society. Cancer Facts and Figures 2018. (https://www.cancer.org/cancer/breast-cancer/non-cancerous-breast-conditions.html ).
Majid, R.A.; Hassan, H.A.; Muhealdeen, D.A.; Mohammed, H.; and Hughson, D.(2017). Breast cancer in Iraq is associated with a unimodally distributed predominance of luminal type B over luminal type A surrogates from young to old age . BMC Women's Health. 17(1)27
Chlebowski R.T.; Rohan T.E.; Manson J.E.; Aragaki A.K.; Kaunitz A.; and Stefanick M.L.(2015). Breast cancer after use of estrogen plus progestin and estrogen alone: analyses of data from 2 Women’s Health Initiative randomized clinical trials. JAMA. Oncol. 1:296–305.
John, T.; Schousboe, M.D.; Kerlikowske, K.; Loh, A.; and Steven, R. (2011). Personalizing Mammography by Breast Density and Other Risk Factors for Breast Cancer: Analysis of Health Benefits and Cost-Effectiveness. Ann Intern Med. 155(1):10-20.
KLEIN, S.M.D.;(2005). Evaluation of Palpable Breast Masses . Am Fam Physician j., 71(9):1731-1738.
Berg, W.A.; Campassi, C.I; and Ioffe, O.B. (2003). Cystic lesions of the breast: sonographic-pathologic correlation. Radiology. 227:183–91.
Bailey, H.; and Love, M. (2008). short practice of surgery. 25th ed., B Hodder Education, an Hachette UK company, P: 838.
KLEIN, S.M.D.;(2005). Evaluation of Palpable Breast Masses . Am Fam Physician j., 71(9):1731-1738.
Habib, O.S.; Hameed, L.A.; Ajeel, N.A.; Al-Hawaz, M.H.; Al-Faddagh, Z.A.; Nasr, G.N.; Al-Sodani, A.H.; Khalaf, A.A.; Hasson, H.M.; Abdul-Samad, A.A.; (2016). Epidemiology of Breast Cancer among Females in Basrah. Asian Pac J Cancer Prev., 17: 191-195
Alghamdi, I.G.; Hussaina, I.I.; Alghamdi, M.S.; and El-Sheemy, M. (2015). Early marriage is a potential risk factor for female breast cancer in the Eastern Region of Saudi Arabia. American Journal of Research Communication . 3(7): -23.
Alsanabani, J.A.; Gilan, W.; and Saadi, A.A.(2015). Incidence data for breast cancer among Yemeni female patients with palpable breast lumps. Asian. Pac. J. Cancer. Prev., 16:191-194.
Al-Amri, F.A.; Saeedi, M.Y.; Al-Tahan , F.M. ; Ali, A.M.; Alomary ,Sh.A.; Arafa,M.; Ibrahim. A.K.; and Kassim, K.K.(2015). Breast cancer correlates in a cohort of breast screening program participants in Riyadh, KSA. Journal of the Egyptian National Cancer Institute. 27: 77–82.
Al Nemer, A. (2017). The pathological profile of Saudi females with palpable breast lumps : knowledge that guide practice. S.J.H.S. 6(2): 92-95.
Willett, W.C.; Tamimi, R.M.; Hankinson, S.E.; Hazra, A.; Eliassen, A.H.; Colditz, G.A. (2014). Diseases of the Breast. Nongenetic factors in the causation of breast cancer. 5th ed. Philadelphia, PA: Lippincott, Williams & Wilkins; In: Harris JR, Lippman ME, Morrow M, Osborne CK. 211-267.
Nelson, H.D.; Zakher, B.; Cantor,A.; Fu, R.; Griffin, J.; O'Meara, E.S.;et al. (2012). Risk factors for breast cancer for women aged 40 to 49 years: a systematic review and meta-analysis. Ann Intern Med. 156(9):635-648
Guo1, J.; Huang, Y.; Yang, L.; Xie, Z.; Song, Sh.; Yin1, Y.; Kuang, L.; and Qin, W.(2015). Association between abortion and breast cancer: an updated systematic review and meta-analysis based on prospective studies. Cancer Causes Control. 26(6): 811-819.
Russo, J.; and Russo, I.H. (1987) Biological and molecular bases of mammary carcinogenesis. Lab Invest., 57:112–137.
Beaber, E.F.; Buist, D.S.; Barlow, W.E.; Malone, K.E.; Reed, S.D.; and Li, Ch. (2014). Recent Oral Contraceptive Use by Formulation and Breast Cancer Risk among Women 20 to 49 Years of Age. CAN. Res., 74(15) 4078- 4089.
Eliassen, A.H.; Coldit, G.A.; Rosner, B.; and Hankinson, S.E. (2006). Tubal sterilization in relation to breast cancer risk. Int J Cancer. 118(8):2026-2030.
Majid, R.A.; Hazha A Mohammed, H.A.; Saeed, H.M.; Safar, B.M.; Rashid, R.M.; and Hughson, M.D (2009). Breast cancer in kurdish women of northern Iraq: incidence, clinical stage, and case control analysis of parity and family risk. BMC Women's Health. 9:33.
Vendhan Gajalakshmi1,V.; Mathew, A.; Brennan, P.; Balakrishnan Rajan, B.; Kanimozhi1,V.C.; Mathews, A.; Mathew, B.S.; and Boffetta, P.(2009). Breastfeeding and breast cancer risk in India: A multicenter case-control study. Int. J. Cancer. 125: 662–665.
Lee, A.H. (2005). Why is carcinoma of the breast more frequent in the upper outer quadrant? A case series based on needle core biopsy diagnoses. Breast. J. 4(2): 151-152.
Chang, T.; Hsu, H.; Chou, Y.; Yu, J.; Hsu, G.; Huang, G.; and Liao, G. (2015). The Values of Combined and Sub-Stratified Imaging Scores with Ultrasonography and Mammography in Breast Cancer Subtypes. PLOS ONE j., 10(12): 1-10.
Alsanabani, J.A.; Gilan, W.; and Saadi, A.A.(2015). Incidence data for breast cancer among Yemeni female patients with palpable breast lumps. Asian. Pac. J. Cancer. Prev., 16:191-194.
Westenend, P.J.; Sever, A.R.; Beekman, D.; Volder, H.J.; and Liem, S.J.(2001). A comparison of aspiration cytology and core needle biopsy in the evaluation of breast lesions. Cancer. 93:146–50.