Zinc toxicity associated with hydatid cyst infection among patients in Nasseriyah city \ Thiqar province , south Iraq


  • Amal KH. Khalaf


   Hydatidosis is endemic disaese in south of Iraq , zinc level are detected in sera of patient  and hydatid cyst fluid by atomic absorption technique in colleges of Basrah university , the present study found that the zinc levels were increase in sera of patient  when compare with control whom are not infected with disaese . so the levels of zinc are also increase or high in hydatid cyst fluid . 


Moraitaki, P.; Roussi, P.; Emmanouil, Y. Pechlivanidou, R.; Bitsakou, C.; Konstantinou, M. and Marosis, K. (2010). Pulmonary echinococcosis presenting as a pulmonary mass with fever and haemoptysis; a case report. Pneumon. J. 23, (2): 180 – 183.

Morar , R. and Feldman , C. (2005). Pulmonary echinococcosis . Eur. Respir. J. , 21 : 1069 – 1077.

Wastney, M.E.; Aamodt, R.L.; Rumble, W.F. and Henkin, R.I. (1986). Kinetic analysis of zinc metabolism and its regulation in normal humans. Am J Physiol, 251: R398-R408.

Aggett, P.J. (1994). Aspects of neonatal metabolism of trace metals. Acta Paediater Supp, 402: 75-82.

Shaeffer, G.L. (2006). Evaluation of basic zinc chloride as a zinc source for cattle. M.Sc thesis in North Carolina State University. Animal Science. Raleigh.

Whitehouse, R.C.; Prasad, A.S.; Rabbani, P.I. and Cossack, Z.T. (1982). Zinc in plasma, neutrophils, lymphocyte and erythrocytes as determined by flameless atomic absorption spectrophotometry. Clin Chem, 28: 475-480.

Ohno, H.; Roi, R.; Yamamura, K.; Lizuka, S. and Taniguchi, N. (1985). A study of zinc destitution in erythrocytes of normal humans. Blut, 50:113-116.

Bently, P.J. and Grubb, B.R. (1991). Experimental dietary hyperzincurea tissue deposition of excess zinc in rabbits. Trace Elem Med, 8(4): 202-207.

Barbier, O,; Jacquillet, G.; Tauc, M.; Cougnon, M. and Pougeol, P. (2005). Effect of Heavy Metals on, and Handling by, the Kidney. Nephron physiol; 99: Pp.105-110.

Mahdi, J. ; Mohammad H. Al-Jawher; and Mahdi, N. K. (2010). Zinc and copper levels in hydatid cyst fluid and patient’s blood . J. Pak. Med. Assoc. 60 (7) : 580-581.

Mahdi NK, Al_Baldawi ,F.A. and , Benyan, A.K. (1996) .Immunoglobulin levels in sera and cyst fluid of human hydatidosis. Med. J. Basrah Univ. , 14: 91-9.

Ozen N, Celik C, Ozkan K, Malazgirt Z, Isimer A, Sayal A. Trace elements in hydatid disease. J Trace Elem Electrolytes Health Dis 1992; 6: 67-70.

Julie, A.I.; Andre, M.; Gillian, L.; Kevin, F. and Louis, D.W. (2003). Element of caution: a case of reversible cytopenias associated with excessive zinc supplementation. CAMJ. 22; 169(2).

Khalaf ,A. KH. (2012). In vitro and in vivo studies of secondary metabolites extracted from some algae against protoscolices of Echinococcus granulosus in laboratory mice Balb/C strain in comparison to albendazole activity . PhD Thesis, College of Education . , Basrah University.

Al – Mobarak, Z.A. (2006). Effect of peel extracts of Punica fruits on on echinococcosis of Echinococcus granulosus . M. Sc. Thesis, College of Education . , Kufa University, (In Arabic).

Settelmine C.T. and Matrone, G. (1967). In vivo Effect of Zinc on Iron Turnover in Rats and Life Span of the Erythrocyte. Journal of Nutrition Vol. 92 No. 2 June, Pp.159 – 164.

De Oliveira, F.S.; Viana, M.R. and Antonio, A.R. (2001). Differential effect of lead and zinc on inhibitory avoidance learning in mice. Braz J Med Biol Bes 34:117-120.

Srivastav, S. K.; Murti, R. C. And Gupta Vinod , C . (2011). Quantitative Analysis of Trace Elements In Fasciolopsis buski and Gastrodiscoides hominis IJCPR,; 2(3):161-168

Fraga CG. (2005) . Relevance, essentiality and toxicity of trace elements in human health. Mol Aspects Med. 2005; 26(4–5): 235–24.