lINTRAOPERATIVE INTRAVITREAL TRIAMCINOLONE ACETONIDE DURING CATARACT SURGERY FOR THE PROPHYLAXIS AND MANAGEMENT OF POSTOPERATIVE DIABETIC MACULAR EDEMA

Authors

  • Wajida Saad Bunian Ophthalmological Dep. , Thi-Qar University , Medical College

Keywords:

Phacoemulsification, diabetic macular edema, Intravitreal Triamcinolone injection

Abstract

Cataract extraction in diabetic patients is commonly indicated, both for visual rehabilitation and for improved visualization of the fundus. Unfortunately the visual prognosis for diabetic patients undergoing cataract surgery is guarded, mainly because of the risk for worsening retinopathy levels and exacerbation of macular edema. The Aim of this study is to evaluate the efficacy of intravitreal Triamcinolone acetonide injected during cataract surgery in the prophylaxis and management of postoperative macular edema following uneventful cataract surgery in diabetics. The study included 2 groups, Group A included 15 patients divided into 2 subgroups 1)-Diabetic patients without any excising  macular oedema., 2)-Diabetic patients with pre-existing macular edema.  Patients in Group A were subjected to phacoemulsification with Posterior chamber intraocular lens implantation. Subjects and methods:  Group B included 15 diabetic patients with or without preoperatively existing macular edema including patients with previous macular laser treatment with visually significant cataract. Patients were subjected to Phacoemulsification with PCIOL implantation and Intravitreal triamcinolone injection (dose of 8 mg in 0.2 ml will be injected slowly through the inferior pars plana). Results: The results of this study showed that phacoemulsification with intravitreal TA in patients with CSME appears to be a safe intervention to avoid the postoperative exacerbation of the edema in patients with dense cataract precluding macular laser treatment. TA may serve as mean to control postoperative inflammation and prevent exacerbation of the macular edema. Postoperative laser treatment may be needed in some cases to augment the effect of intravitreal TA.

References

Abelson MB, Smith LM, Ormerod LD: Prospective, randomized trial of oral piroxicam in the prophylaxis of postoperative cystoid macular oedema. J ocular Pharmacology. 1992; 5:147-153.

Bresnick GH : Diabetic maculopathy: A critical review highlighting diffuse macular edema. Ophthalmology. 1983; 90:1301-1317.

Charters L: CME can reduce visual acuity after phaco procedures. Ophthalmology. Times.1997; 8:18.

Hee MR, Puliafito CA, Wong C, et al: Quantitative assessment of macular edema with OCT. Arch Ophthalmol. 1995; 36:608-613.

Jonas JB, Sofker A: Intraocular injection of crystalline cortisone as adjunctive treatment of diabetic macular oedema. AM J Ophthalmol 2001 Sep; 132(3): 425-7.

Klein A, et al: The Wisconsin Epidemiological study of Diabetic retinopathy. IV. Diabetic macular oedema. Ophthalmology. 1984; 91:1464-1474.

Nussenblatt RB, Kaufman Sc, Palestinr AG: Macular thickening and visual acuity: measurements in patients with cystoid macular oedema. Ophthalmology.1994; 101:1134-1139.

Pollack A, Leiba H, Bukelman A, and Oliver M: Cystoid macular oedema following cataract extraction in patients with diabetes. Br J Ophthalmology 1992 Apr; 76(4): 221-224

Pollack A, Dotan S, Oliver M: Progression of diabetic retinopathy after cataract extraction. Br J Ophthalmology 1991; 75:547-551.

Pollack A, Leiba H, Bukelman A, Abraham S and Oliver M: The course of diabetic retinopathy following cataract surgery in eyes previously treated by laser photocoagulation. Br J Ophthalmol. 1992; 76: 228-231.

Wingate RJ, Beaumont PE.: Intravitreal triamcinolone and elevated intraocular pressure. Aust N Z J Ophthalmol. 1999 Dec; 27(6):431-2.

Yannuzzi LA, Wright PL, Wilkinson CP, Balyeat HD, et al: Angiographic cystoid macular oedema after posterior chamber lens, implantation. Arch Ophthalmol 1988; 106:740-744.

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Published

2021-06-13

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