Co-incidental urolithiasis in patients with gall stones

Authors

  • Safa El-dean S.Nema M.B.CH.B. F.I.C.M.S. Assistant Professor, surgical department ,Kufa Collage of medicine

Abstract

Background Gall stones and renal stones are one of the common pathologies recorded all over the world , there are many types for both renal and gall stones as well as different etiology and causing different signs  and symptoms . Objective.  The study planned to determine if there is significant statistical association between the coexistence of renal stones  with gall stones . Patients and Methods  140  patients presented with gall stones from the period of January 2007 until march 2008 in out patient clinic, 117(83.5%) patients where females and 23(16.5%) where males, all the patients examined by ultrasound for both renal and gall stones and some patients with renal stones examined by KUB x-ray and/or IVU, records of all patients reviewed for age, gender, gross appearance of both types of stones post operatively (for those who were operated) and for those patients passing renal stones per urethra and correlated with the type of gall stone that seen post operatively, the patients underwent different modalities of treatments, by surgery (open or laparo- scopic cholecystectomy ),(nephrolithotomy),or conservative for both types of stones.    Results.  Regarding the gall stones, surgical treatment done for  118 patients, 100 of them by laparoscopic cholecystectomy and open cholecystectomy for 18 patients, while 22 patients treated conservatively, and regarding the renal stones 12 patients of them operated during the course of study, and 20 patients of them passing their stones per urethra, and all these stones seen grossly, the other patients treated conservatively, the study shows positive presence of renal stones in 95 (67.9%) patients of total number, the coincidence was noticed to increase with age (p value >0.05) and with pigmented gall stones and female sex (p value <0.05 for both). Conclusion There is significant positive coincidental presence of renal stones in patients with gall stones in this study. Aim of Study This study planned to determine the statistical relation ship between coincidental presence of renal stone(s) and gall stone(s) after observing a remarkable incidental occurrence of both of them, a step that hinders the search for their etiological factors.    

References

Guido R. Zanni , Ph.D. management and prevention of kidney stones , pharmacy times – August 2006.

Farnbacher MJ, Shoen C, Rabenstein T, et al. Pancreatic duct stones in chronic pancreatitis : criteria for treatment intensity and success. Gastrointest Endosc 2002; 56:501-605(PubMed: 12297764).

Beckingham IJ , Rowlands BJ , post cholecystectomy problems , In Blumgart H , ed surgery of liver and biliary tract . 3rd ed . London , WB saunders 2000 .

Nakeeb A. Comuzzie AG. Martin L. et al : Gall stones : Genetics versus environment. Ann Surg 235:842,2002.

Sherlock , S. and Dooley , J.(eds) (2001) Disease of Liver and Biliary System, 11th edn. Blackwell publishing, Oxford.

Blumgart, L.H. and Fong, Y. (eds) (2000) Surgery of Liver and Biliary Tract, 3rd edn. W.B. Saunders, London.

Klein AS , Lillemoe KD , Yeo CJ, et al : Liver, biliary tract, and pancrease, in O Leary JP(ed) : physiologic bases of surgery . Baltimore : Williams and Wilkins , 1996 p 441 .

. Stewart L, Oesterle AL, Erdan I, et al: Pathogenesis of pigmented gall stones in western societies : the central role of bacteria, J Gastrointest. Surg. 6: 891 , 2002.

G.P. Vanberge Henegouwen , N.G. Venneman, P. Portincasa, A.Kosters, K.J. Van Erpecum, A.K. Groen. , Relevance of hereditary defects in lipid transport proteins for the pathogenesis of cholesterol gall stone disease . Scandinavian journal of gastroenterology , vol. 39 , issue 1 , supplement 241 , 2004 , page 60-69 .

Boyer J : Bile secretion-models, mechanism, and malfunctions. A perspective on the development of modern cellular and molecular concepts of bile secretion and cholestasis. J Gastroenterol 31:475,1996.

age

Kumar Muneesh , Goyal B.B. , Mahajan M., Singh S. , Role of iron deficiency in the formation of gall stones . Indian journal of surgery vol. 68 issue 2 page 80-83, 2006 .

Thistle JL, Schoenfield LJ: Lithogenic bile among young indian women: Lithogenic potential disease with chenodeoxycholic acid, N Engl J Med 284: 177, 1971.

AL-Jiffry BO, Shaffer EA, Saccone GT, et al: Changes in gall bladder motility and gall stone formation following laparoscopic gastric banding for morbid obesity. Can J Gastroenterol 17:169,2003.

K.J. Van Erbecum , G. A. Van Berge , Hene Gouwen , Gall stones in intestinal diseases (Gut) 1999 , issue 44 , page 435- 438 , (March) . Department of gastroenterology , university hospital , Utrecht , G.A. Utrecht , Netherlands .

Ackermann D et al: Influence of calcium content in mineral water on chemistry and crystalline conditions in urine of calcium stone formers . Eur Urol 1988 ;14:305.

Tiselius HG: Metabolic evaluation of patients with stone disease. Urol Int 1997;59:131.

Parivar F, Low RK, Stoller ML, The influence of diet on urinary stone disease. J Urol 1996; 155:432.

Hatch M: Oxalate status in stone formers , Two distinct hyperoxaluric entities. Urol Res 1993:21:55.

Ryall RL: The scientific basis of calcium oxalate urolithiasis: predilection and precipitation, promotion and proscription. World J Urol 1993; 11; 59.

Ohman S Larsson L, Tiselius HG; Clinical significance of phosphate in calcium oxalate renal stones. Ann Clin Bioch 1992; 29; 59.

Asplin JR: Uric acid stones. Semin Nephrol 1996; 16: 412.

Yu TF: Urolithiasis in hyperuricemia and gout. J Urol 1981; 126:424.

Gupta M, Bolton DM, Stoller ML: Etiology and management of cystine lithiasis. Urology 1995; 45: 344.

Kario K, Matsuo T, Tankawa H: Xanthine Urolithiasis: Ultrastructure analysis of renal and bladder calculi. Int Urol Nephrol 1991; 23: 317.

Lee MH et al: Silica stone development due to long time oral trisilicate intake. Scand J Urol Nephrol 1993; 27: 267.

Dooley DP, Callsen ME, Geiling JA: Triamterene nephrolithiasis. Milit Med 1989; 154: 126.

Fellstrom B et al: Dietary habits in renal stone patients compared with healthy subjects. Br J Urol 1989; 63: 575.

Hojgaard I, Tiselius HG: The effects of citrate and urinary macro molecules on the aggregation of hydroxylapatite crystals in solutions with a composition similar to that in distal tubule. Urol Res 1998; 26: 89.

Pak CY: Citrate and renal calculi: New insights and future directions. Am J Kidney Dis 1991; 17: 420.

Hall MK et al: Renal calculi in spinal cord injured patient: association with reflux, bladder stones, and Foley catheter drainage. Urology 1989; 34: 126.

Vaidyanathan S et al: Recurrent bilateral renal calculi in a tetraplegic patient. Spinal Cord 1998; 36: 454.

Gutman AB , Yu TF: Uric acid nephrolithiasis . Am. J. Med 1968 45:756

Randall A: The origin and growth of renal calculi. Ann Surg 1937 ; 105 : 1009.

Carr RJ : Etiology of renal calculi : micro- radiographic studies . In Hodgkinson A, Nordin BEC (eds) : Renal stone research symposium London , J&A Churchil Ltd, 1969, P 123.

Downloads

Published

2021-09-15

Issue

Section

ARTICLE