• Jamal Ahmed Abdul- Barry Department of Biochemistry , College of Medicine, University of Basrah
  • Lamia M. Al Naama Department of Biochemistry , College of Medicine, University of Basrah
  • Hassam Odah D. ALAmari Thi Qar Health Directory
Keywords: Calcium, phosphate, protein, alkaline phosphatase, elderly


Objective: The aim of this study was to investigate the value of serum calcium (Ca), phosphate (P), total protein (TP) and alkaline phosphatase (AIP) activities in elderly patients, to know the levels of those biochemical p parameters and to clarify the relationships of these finding with the diseases that having specially over the life     Study design: A prospective case control study conducted at the biochemistry Department, through a period of 1 year from the first of October 1999 till the end of October 2000.Base line samples were collected to measure S. Ca, P,TP and AIP activities in 110 elderly patients aged 72± 6.5 years (62 males and 48 females) and the effects of biological factors (age, sex, and weight) and large set of pathological conditions were examined and for comparison, another 100 subjects aged 68±8 years (63 males and 37 females) whom, were found free of any disease and or alcoholic and smoking habit considered as a control group. Results: The results of the study showed a significant decreased (p<0.05) in the concentrations of S.Ca and TP and a significant increased (P<0.05) in the concentrations of S. P and AIP activity in hypertensive and in patients how have renal failure. A significant increased (P<0.05) in the S.Ca, P and AIP activity and a non – significant decrease (P>0.05) in the TP level, were observed in the patients having bone and joint diseases. The values of S. P in the patients having heart disease shows a significant increased (P<0.05) and non – significant changes (P>0.05) in the concentrations of serum Ca, TP and AIP activity is often considered. Non significant alterations (P>0.05) was observed in those biochemical parameters in relation to diabetes mellitus or other pathological conditions. Conclusion:    We conclude that, the measurements of those biochemical's parameters in elderly populations was useful to know some of theories of aging that might take place in the cell, an organ or total organism with a passage of time, and also the sequential or progressive change in an organism that leads to an increased risk of debility, disease and death.


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