Impact of Rheumatoid Arthritis on Some Immunological Aspects and Lipid Profile of Type 2 Diabetes in Nasiriyh City, Iraq
Keywords:
Rheumatoid arthritis, Diabetes mellitus, 1,5-Anhydroglucitol, HbA1c, lipid profileAbstract
Background: Rheumatoid arthritis A systemic autoimmune disease causes polyarthritis and organ damage. Insulin resistance is associated with inflammatory indicators. Glycated hemoglobin (HbA1c), a biomarker for continuous glucose monitoring, and 1,5-ahydroglucitol are found in the blood in high but consistent amounts under normal conditions. Disease-modifying anti-rheumatic drugs raise lipid levels. The aim of study was to evaluate whether or not there is a relationship between rheumatoid arthritis and diabetes mellitus, using many immunological and biochemical criteria. Methods: Current research on rheumatoid arthritis and diabetes mellitus was conducted at Al-Nasriyah Education Hospital with one hundred blood samples collected from patients. Divided into four groups, this study employed immunological (1,5-anhydroglucitol) and biochemical (random blood sugar, total triglyceride, and total cholesterol) data. Result: In the current study, the control group had more 1,5-anhydroglucitol than the patients. significant increases in random blood sugar, triglyceride, total cholesterol, and HbA1c in patients with only diabetes and patients with both diseases, as well as a significant difference between rheumatoid patients and controls. Conclusion: Patients with type 2 diabetes mellitus who have low 1,5-ahydroglucrtol levels may be strong predictors of diabetes mellitus. Rheumatoid arthritis patients may have an effect on lipid profiles, HbA1c percentages, and 1,5-ahydroglucrtol levels, which should be evaluated throughout the illness.References
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