Reproductive Effects of some trace elements On Male Infertility In Thi-Qar Governorate/Iraq
Keywords:Seminal fluid, Trace Element, Azoospremia
The present study was carried out on 50 infertile males whose age range between (19-49) year and 16 male, who were apparently healthy, as a control group whose age range between (18-49) year.
The studied males were classified into two groups according to their case health to infertile male and fertile male.
The parameters measured were seminal fluid levels lead, cadmium, zinc, copper, chromium, magnesium, iron and cobalt. These parameters were estimated in seminal fluid of patients and control group.
The results shown a highly significant different in levels of lead element(7.541a, 0.056b ), cadmium element(0.023a, 0.007b), zinc element(1.275a, 0.054b ), chromium element(0.408a, 0.090b), iron element(2.172a, 0.148b), cobalt element(0.022a, 0.008b), in primary infertile males when compared with in secondary infertile males(a: primary, b:secondry).The results shown a highly significant different in levels of lead element, cadmium element, zinc element, chromium element, iron element, cobalt element, in infertile men when compared with fertile men.
The results illustrated highest level of concentrations elements in measurements was lead element levels and cadmium levels in infertile males when compared with control group.
As well as lower levels of concentration metals was cobalt element levels in infertile males when compared with control group.
Geidam AD, tawe kdt, Adebayo AEA ET AL. hormonal profile of men investigated for infertility at the university of Maiduguri in northern Nigeria. Singaporemed j, 2008; 49; 538-541.
demetrius jp, male infertility: diagnosis and treatment. J nurse pract, 2006; 2: 298-299.
Ekwere Pd, Archibong EE, Bassey EE et al. Infertility among Nigerian couples as seen in calabar. Port harcout med j, 2007; 2: 35-40.
mathur N, pandey G and jain GC . male reproductive toxicity of some selected metals: a review. J bio sci, 2010; 10: 396-404.
Opsahl ms, Dixon Ng, Robins Er and Cunningham ds Signle us. Multiple semen specimens in screening for male infertility factors. A comparison. Cambridge: Cambridge university press, 2000.
Paulson JD, Asmar P, Saffan DS. Mild and moderate endometriosis. Comparsion of treatment modalities for infertile couples. J Repod Med ,1991; 36: 151-5.
Alloway bj. Heavy metals in soils. New York: john wiley inc, 1990.
Mendiola J., J. M. Moreno, M. Roca, N. Vergara-Juarez, M. J. Martine-Garcia, A. Garcia-Sanchez, B. Elvira-Rendueles, S. Moreno-Grau, J. J. Lopez-Espin, j. Ten, R. Bernabeu and AM. Torres-Cantero, 2011.
Rowe PJ, Comhaire FH, Hargreave TB and Mellows HJ (eds) WHO manual for the standardized investigation and diagnosis of the infertile couple. Cambridge University Press, Cambridge, 1993.
Joffe, M, Infertility and environmental pollution. Advances in Bioscience and biotechnology,2011; 2: 182-197.
Talisman, S, B. Colak, A. Pizent, Jurasovic and P Cvitkovic, Reproductive toxicity of low-level lead exposure in men. Environ Res, 2007;105: 256-266.
Goyer RA and Cherion MG. Ascorbic Acid and EDTA Treatment of Lead Toxicity in Rats. Life Science, 1979; 24: 433-438.
Rowe PJ, Comhaire FH, Hargreave TB and Mellows HJ (eds) WHO manual for the standardized investigation and diagnosis of the infertile couple. Cambridge University Press, Cambridge 1993.
Harnly j. m. multielement atomic absorption with a continuum source, anal. Chem, 1986; 58: 933-943.
Ali R, Birsen A, Hhan O, Bulent A, Hamdi O, Tevfik G. high levels of cadmium and lead in seminal fluid and blood of smoking men are associated with high oxidative stress and damage in infertile subjects 2007.
Spomenka T, Petra C, Jasna J, Alica P, Mirjana G, And Boris R, semen quality and reproductive endocrine function in relation to biomarkers of lead, cadmium, zinc and copper in men, 2000;108: 45-50.
Nahla M Tawfiq, Zina A Marrow, Basil Y Salah. Trace elements in the serum and plasma and their relationship to infertility in Iraq males. Alkindy Col Med J,2007;1: 11-14.