Seroprevalence, Histologic Grades and Stages in Breast Cancer Patients with Toxoplasmosis in ThiQar Province/ Southern Iraq
Keywords:
Toxoplasmosis, breast cancer, serology, histological gradeAbstract
Abstract: Toxoplasmosis is one of the most common diseases in the world. It is found allover the world and affects a considerable proportion of people. It is known for being
asymptomatic and affects all warm-blodded animals, including humans. T. gondii parasite is
responsible for the disease. Patients with weakened immune systems, such as those with AIDS or
cancer, are most at risk for infection. The study's main goal is to detect T. gondii infection in BC
patients using the serological method (ELISA). This study involves measuring the T.gondi (IgG)
levels of 150 patients with breast cancer whom entered oncology center of Al-Haboubi Teaching
Hospital in Nasiriya City (southern Iraq ), and 54 healthy controls. The results demonstrated that
47.3% of breast cancer patients were infected with T. gondii compared with the control group
(33.3%). The age group with the highest infection rate was (41–50) years old among BC patients
infected with T.gondii (38%), while the age range between 71–80 years old had the lowest
infection rate (4%).Additionally, there was a higher rate of toxoplasmosis among patients with
breast cancer whom were lived in urban (57.75%) compared with those living in rural. The
results showed a high rate of breast cancer patients with toxoplasmosis (59.15%) in grade 2
compared with other grades. Stage III of breast cancer showed a high rate of infection with
toxoplasmosis (66.19%) compared with other stages
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