Comparative Analysis of Azithromycin Resistance in Gram Positive Bacteria Pre- and Post- COVID-19 Pandemic
Keywords:
COVID-19, drug resistance, Azithromycin, AntibacterialAbstract
Background: On the first day of the SARS-CoV2 pandemic, azithromycin (AZM) was one ofthe most commonly utilised drugs, even though there is no scientific evidence to support its
usage in treating COVID-19. Because it encourages the establishment of drug-resistant bacterial
strains, which makes it more tough to successfully treat a range of bacterial infections, its free
egress has generated worries about public health. Perfect for learning how to combat COVID-19
infections using antibiotics that are effective against azole-group fever (AZM)-resistant bacteria.
Methods: In order to mimic cases of tonsillitis, pharynx infections, or respiratory tract
infections, a control group consisting of 25 samples were used from healthy individuals as a
control group and 37 bacterial isolates was maintained apart from cases that had previously
contracted the corona virus. Ten scholarly articles were completely reviewed. All extra criteria
were met by studies published between 2015 and 2023 that dealt with AZM resistance in bacteria
during the treatment of bacteriosis or the fight against COVID-19.
Results: indicated that out of 25 control samples, 13 (or 52% of the total) responded positively
to AZM whereas 12 (or 48% of the total) were resistant. In addition, 26 (70.27%) of the bacteria
that were isolated were completely resistant to the antibiotic, whereas 11 (29.72%) of the isolates
were found to be susceptible.
Conclusions: Implicit bacterial resistance to AZM is directly correlated with the careless use
of this medication. Because AZM, an antibiotic drug, is widely used to treat a variety of bacterial
diseases, the emergence of resistance bacteria poses a significant threat to public health.
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