Portable Microfluidic Devices-Based Nanosensors for Detection of Mercury and Cadmium in Blood Plasma
DOI:
https://doi.org/10.32792/jmed.2025.29.32Keywords:
Heavy metals, Microfluidics, Nano structure, Hg²⁺ detection, Cd²⁺ detection.Abstract
Heavy metals such as cadmium (Cd²⁺), mercury (Hg²⁺), and lead (Pb²⁺) areconsidered some of the most dangerous environmental pollutants due to their high
toxicity and cumulative effects on human health and the environment. With the
increasing need for precise, rapid, and highly sensitive detection technologies, the
integration of nanomaterials with microfluidic techniques has emerged as one of
the effective solutions in developing advanced sensing systems
Nanomaterials provide unique properties such as high surface area and distinctive
electrochemical and optical characteristics, enabling them to capture heavy metal
ions with exceptional efficiency. When integrated into microfluidic platforms
(Lab-on-a-Chip), a precise analytical environment is achieved, enabling detection
using minimal amounts of samples and reagents, with a short analysis time.
These systems are characterized by their ability for on-site detection. Various
characterization measurements such as UV, XRD, FESEM, TEM, FT-IR, and
Zeta Potential were conducted to characterize the nanoparticles. The study
indicated that the best elements used for detecting heavy metals in blood plasma
are zinc oxide and copper. This integration is considered one of the promising
recent trends in the field of environmental monitoring and precise medical
analysis.
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