Main Article Content

Abstract

Air pollution is a serious health problem in the world especially to those who
already have cardiorespiratory illnesses. Although the association between
exposure to pollution and health exacerbation is well-established, the current
interventions in the area of public health are not customized by taking into account
personal vulnerability, geographic position, and daily routine activities. Existing
studies are mainly concentrated on predictive modeling based on machine
learning or macro-level resource optimization, but do not combine these two
measures into practical and personalized guidance. This work fills this critical gap
by hypothesizing and confirming the new hybrid machine learning-optimization
model to produce individual alerts on air pollution exposures. An artificial group
of 100 patients with asthma, COPD and ischemic heart disease is modeled in 90
days. The first stage entails the training of a logistic regression model to estimate
short-term exacerbation risk (with an AUC of 0.979 and an accuracy of 0.961).
This risk score is then inputted into a second-stage mixed-integer linear
programming resulting in the production of optimal daily action plans. The
findings indicate that the framework effectively orders viable interventions in a
successful completion of an average personal exposure reduction of 39.4 percent
of all case studies without violating individual involvement restrictions and
interests, making it a viable paradigm of precision environmental health.

Keywords

Air Pollution, Cardiorespiratory Health, Machine Learning, Optimization, Personalized Medicine.

Article Details

References

  1. Tompra, K.V., Papageorgiou, G. and Tjortjis, C., 2024. Strategic machine learning optimization for cardiovascular disease
  2. prediction and high-risk patient identification. Algorithms, 17(5), p.178.
  3. Aliyu, D.A., Akhir, E.A.P., Saidu, Y., Adamu, S., Umar, K.I., Bunu, A.S. and Mamman, H., 2024. Optimization techniques
  4. for asthma exacerbation prediction models: a systematic literature review. IEEE Access.
  5. in
  6. Di Guardo, A., Trovato, F., Cantisani, C., Dattola, A., Nisticò, S.P., Pellacani, G. and Paganelli, A., 2025. Artificial
  7. Intelligence
  8. Cosmetic Formulation: Predictive Modeling for Safety, Tolerability, and Regulatory
  9. Perspectives. Cosmetics, 12(4), p.157.
  10. Hoghooghi Esfahani, H., Toyonaga, S. and Oyibo, K., 2025. The application of explainable artificial intelligence in the
  11. prediction, diagnoses, treatment, and management of chronic diseases: A systematic review. Digital Health, 11,
  12. p.20552076251355669.
  13. Kumar, C.S. and Thangaraju, P., THE IMPACT OF EVOLUTIONARY ALGORITHMS IN DATA
  14. MINING. Interdisciplinary Research Innovations in Science and Humanities, p.159.
  15. S. Nadweh, F. Al-Omari, N. T. Thannon, J. F. Tawfeq, A. Ibrahim and Z. A. Jaaz, "A Reinforcement Learning Framework
  16. for Intelligent Detection of Bad Data in Power System State Estimation," 2025 3rd International Conference on Cyber
  17. Resilience (ICCR), Dubai, United Arab Emirates, 2025, pp. 1-7, doi: 10.1109/ICCR67387.2025.11292295.
  18. S. Nadweh, A. Shawkat Abdulbaqi, J. Fadhil Tawfeq and A. Dheyaa Radhi, "AI-Powered Smart Cooling System for Solar
  19. Panels: Enhancing Efficiency Through Weather Forecasting and Adaptive Control," 2025 3rd International Conference on
  20. Business Analytics for Technology and Security (ICBATS), Dubai, United Arab Emirates, 2025, pp. 1-6, doi:
  21. 1109/ICBATS66542.2025.11258170.
  22. S. Nadweh, A. K. Abdulsahib, R. Almajed, M. Mahfuri and J. F. Tawfeq, "Evaluation of Energy Storage Strategies Using
  23. Artificial Intelligence to Enhance the Stability of Power Grids Integrated with Renewable Energy," 2025 3rd International
  24. Conference on Business Analytics for Technology and Security (ICBATS), Dubai, United Arab Emirates, 2025, pp. 1-9, doi:
  25. 1109/ICBATS66542.2025.11258246.
  26. Nadweh, S., Al Sayed, I.A., Abdulbaqi, A.S., Essa, R.O., Sham, R., Gheni, H.M. and Radhi, A.D., 2025. A Hybrid
  27. Approach Based on Artificial Intelligence and Model Predictive Control for Enhancing Stability and Efficiency of
  28. Complex Dynamic Systems. Journal of Robotics and Control (JRC), 6(5), pp.2426-2435.
  29. Nadweh, S., Elzein, I.M., Mbadjoun Wapet, D.E. and Mahmoud, M.M., 2025. Optimizing control of single-ended primary
  30. inductor converter integrated with microinverter for PV systems: Imperialist competitive algorithm. Energy Exploration &
  31. Exploitation, p.01445987251382002.
  32. Nadweh, S., Mohammed, N., Konstantinou, C. and Ahmed, S., 2025. Operational Performance Assessment of PV-Powered
  33. Street Lighting: A Comparative Study of Different Machine Learning Prediction Models. IEEE Access.
  34. Scimeca, M., Palumbo, V., Giacobbi, E., Servadei, F., Casciardi, S., Cornella, E., Cerbara, F., Rotondaro, G., Seghetti, C.,
  35. Scioli, M.P. and Montanaro, M., 2024. Impact of the environmental pollution on cardiovascular diseases: From
  36. epidemiological to molecular evidence. Heliyon, 10(18).
  37. Yang, J., Lin, Z. and Shi, S., 2024. Household air pollution and attributable burden of disease in rural China: A literature
  38. review and a modelling study. Journal of Hazardous Materials, 470, p.134159.
  39. Kim, J.H., Woo, H.D., Lee, J.J., Song, D.S. and Lee, K., 2024. Association between short-term exposure to ambient air
  40. pollutants and biomarkers indicative of inflammation and oxidative stress: a cross-sectional study using KoGES-HEXA data.
  41. Environmental Health and Preventive Medicine, 29, pp.17-17.
  42. Mao, Q., Zhu, X., Zhang, X. and Kong, Y., 2024. Effect of air pollution on the global burden of cardiovascular diseases and
  43. forecasting future trends of the related metrics: a systematic analysis from the Global Burden of Disease Study 2021. Frontiers
  44. in medicine, 11, p.1472996.
  45. Alhuneafat, L., Al Ta'ani, O., Tarawneh, T., ElHamdani, A., Al-Adayleh, R., Al-Ajlouni, Y., Naser, A., Al-Abdouh, A.,
  46. Amoateng, R., Taffe, K. and Alqarqaz, M., 2024. Burden of cardiovascular disease in Sub-saharan Africa, 1990–2019: an
  47. analysis of the global burden of Disease Study. Current problems in cardiology, 49(6), p.102557.
  48. Bortty, J.C., Bhowmik, P.K., Reza, S.A., Liza, I.A., Miah, M.N.I., Chowdhury, M.S.R. and Al Amin, M., 2024. Optimizing
  49. lung cancer risk prediction with advanced machine learning algorithms and techniques. Journal of Medical and Health
  50. Studies, 5(4), pp.35-48.
  51. Whig, P., Kasula, B.Y., Yathiraju, N., Jain, A. and Sharma, S., 2024. Revolutionizing gender-specific healthcare: harnessing
  52. deep learning for transformative solutions. In Transforming Gender-Based Healthcare with AI and Machine Learning (pp.
  53. -26). CRC Press.
  54. Luo, Z., Tian, J., Zeng, J. and Pilla, F., 2024. Flood risk evaluation of the coastal city by the EWM-TOPSIS and machine
  55. learning hybrid method. International Journal of Disaster Risk Reduction, 106, p.104435.
  56. Bagherabad, M.B., Rivandi, E. and Mehr, M.J., 2026. Machine learning for analyzing effects of various factors on business
  57. economic. Applied Decision Analytics, 2(1), pp.41-54.
  58. Vol., No. , Year, pp.
  59. Liu, S., Du, Z., Wang, G., Zhang, P., Xu, W., Yu, J. and Li, D., 2026. From Traditional Machine Learning Models to
  60. Multimodal Large Models: A Review of Aquaculture. Reviews in Aquaculture, 18(1), p.e70111.
  61. Sun, K., Gu, Y., Wan Fei Ma, K., Zheng, C. and Wu, F., 2024. Medical supplies delivery route optimization under public
  62. health emergencies incorporating metro-based logistics system. Transportation research record, 2678(7), pp.111-131.
  63. Kumar, S., Kumar, S. and Shiwlani, A., 2025. Machine Learning for Labor Optimization: A Systematic Review of Strategies
  64. in Healthcare and Logistics. Pakistan Social Sciences Review, 9(1), pp.631-651.
  65. Biswas, S., Belamkar, P., Sarma, D., Tirkolaee, E.B. and Bera, U.K., 2025. A multi-objective optimization approach for
  66. resource allocation and transportation planning in institutional quarantine centres. Annals of Operations Research, 346(2),
  67. pp.781-825.
  68. Odo, O.K., Gulma, K.A. and Audi, M., 2024. Optimizing last-mile delivery of essential medicines in Nigeria: Insights from
  69. Niger State’s health-care supply chain. Global Health Economics and Sustainability, 3(1), pp.185-196.
  70. Singh, T. and Sinjana, D.Y., 2024. Optimizing Healthcare Logistics with Hybridngs for Blood Bag Delivery Using Drones:
  71. Hybridngs Algorithm [Hybrid Nearest Neighbour, Genetic Algorithm, Simulated Annealing] for Drone Routing”. Available
  72. at SSRN 4840048.
  73. Oluwole, O., Emmanuel, E., Ogbuagu, O.O., Alemede, V. and Adefolaju, I., 2024. Pharmaceutical supply chain optimization
  74. through predictive analytics and value-based healthcare economics frameworks.
  75. Wang, X., Liu, L., Wang, L., Cao, W. and Guo, D., 2024. An application of BWM for risk control in reverse logistics of
  76. medical waste. Frontiers in Public Health, 12, p.1331679.
  77. Ojika, F.U., Onaghinor, O., Esan, O.J., Daraojimba, A.I. and Ubamadu, B.C., 2024. Designing a business analytics model
  78. for optimizing healthcare supply chains during epidemic outbreaks: Enhancing efficiency and strategic resource
  79. allocation. International Journal of Multidisciplinary Research and Growth Evaluation, 5(1), pp.1657-1667.
  80. Luan, R., 2024. Logistics distribution route optimization of electric vehicles based on distributed intelligent
  81. system. International Journal of Emerging Electric Power Systems, 25(5), pp.629-639.
  82. Cao, C., Li, J., Liu, J., Liu, J., Qiu, H. and Zhen, J., 2024. Sustainable development-oriented location-transportation integrated
  83. optimization problem regarding multi-period multi-type disaster medical waste during COVID-19 pandemic. Annals of
  84. Operations Research, 335(3), pp.1401-1447.
  85. Ongesa, T.N., Ugwu, O.P.C., Ugwu, C.N., Alum, E.U., Eze, V.H.U., Basajja, M., Ugwu, J.N., Ogenyi, F.C., Okon, M.B. and
  86. Ejemot-Nwadiaro, R.I., 2025. Optimizing emergency response systems in urban health crises: A project management
  87. approach to public health preparedness and response. Medicine, 104(3), p.e41279.
  88. Mzili, T., Mzili, I., Riffi, M.E., Kurdi, M., Ali, A.H., Pamucar, D. and Abualigah, L., 2024. Enhancing COVID-19
  89. vaccination and medication distribution routing strategies in rural regions of Morocco: A comparative metaheuristics
  90. analysis. Informatics in Medicine Unlocked, 46, p.101467.

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