Antifungal Activities of Alcoholic and Aqeuous Extracts of punica granatum against Some Non-Dermatophytic Fungi

  • Faten Naeem Abbas Microbiology Department-College of Medicine -University of Thi-Qar

Abstract

  A clinical and mycological study of superficial mycosis was conducted on 23 cases (7 males and 16 females) , and  collected from patients (5-50) years old. Direct microscopy by KOH (potassium hydroxide) mount and culture was undertaken to isolate the fungal pathogen in each case.   Non-dermatophyte molds were isolated from 18 cases (78.26%)  and 21 isolates were identified from these cases ; 10 isolates  Candida albicans (47.61%), 5 isolates Rhizopus stolonifer (23.8%), 2 isolates  Penicillium sp. and 2 isolates Aspergillus nidulans (9.5%) respectively, 1 isolate Alternaria alternata and1 isolate Fusarium sp. (4.7%) respectively . Alcoholic & aqueous extracts of the punica granatum (Pomegranate) peels were prepared. The anti-fungal activity of the extracts was evaluated on isolated fungi by means of the agar-well diffusion assay. The Minimum inhibitory concentrations were 10-300 mg/ml against isolated fungi. Their was little difference between the activities of alcoholic extract & aqueous extract. These results suggest the Pomegranate Peels extract which contains active constituents as a promising anti-fungal agent.

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Published
2021-03-24
Section
Articles