Study of Determination and Effect of The Level of Copper, Zinc, Selenium and Body Mass-Index in Hyperlipidemia Patients in Babylon Province

Authors

  • Huda Ahmed Duhaib Department of Biochemistry, College of Medicine, University of Babylon, Iraq
  • Mufeed Jalil Ewadh Department of Chemistry and Biochemistry, College of Medicine, Babylon University
  • Tariq Hussein Mgheer Department of Chemistry and Biochemistry, College of Medicine, Babylon University

Keywords:

hyperlipidemia, zinc, copper, selenium, body mass index

Abstract

Background:  Hyperlipidemia is common in public, the link between trace elements and Hyperlipidemia is not clearly studied. For humans, copper, zinc and selenium are essential trace elements in nutrients and required in very small quantities for various biological functions. During disease, trace elements used for diagnosis, it is essential to distinguish whether the balance is altered in free or bound elements. Objective: For the assessment of copper, zinc, selenium and body mass index level and to examine the correlation between parameters and study the probable relation of them with diagnosis of hyperlipidemia in Babylon province. Materials and Methods:  Cu, Zn and Se were estimated in one  hundred subjects; 50 patients with hyperlipidemia and 50 healthy subjects were participated in this study. Patients and control groups with an age ranged between (19-75) years. The level of Zn and Cu and Se were assessed in serum by Flameless Atomic absorption spectrophotometer method. Results: Serum levels of selenium and zinc displayed a significant decrease, while serum copper significantly elevated (p < 0.001) in hyperlipidemia patients. On the other hand, selenium and zinc correlated significantly with body mass index. Conclusion:  Among hyperlipidemia patients in Babylon province, the variability in some trace elements indicate the significant relationship with hyperlipidemia.  

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2023-10-02

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