Study of Some New Pt(II) Complex Involving Quercetin, Naringen, and Apigenin: Synthesis, Characterization, Antimicrobial and Antioxidant Activities

Authors

  • Lateef Sahib Thamer Department of Chemistry, College of Science, University of Basrah, Basrah, Iraq
  • Sameerah Ahmed Zearah Department of Chemistry, College of Science, University of Basrah, Basrah, Iraq
  • Adil Ali Al-Fregi Department of Chemistry, College of Science, University of Basrah, Basrah, Ira

Keywords:

Platinum(II), Structural analysis, Antimicrobial activity, GC-MS Analysis, Anticancer activity

Abstract

A Pt(II) complex including quercetin, naringinin, and apigenin was made in the
current study, and its structural characteristics were determined utilizing spectrum
techniques. The Pt(II) complexes have been investigated for their ability to combat
microorganisms and breast cancer. According to the findings of the investigation into
the complex's antibacterial action, Staphylococcus aureus, Escherichia coli, Candida
alblicans, and Aspergillus niger were all considerably impacted. Using the 2,2-
Diphenyl-1-picrylhydrazylradical scavenging activity assay (DPPH), it was examined
whether the Pt(II) complexes have antioxidant qualities and may be useful in the
treatment of disorders caused by free radicals. These novel complexes may be
exploited for these therapeutic purposes, according to this study's findings.

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2023-10-30

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