Main Article Content
Abstract
current study, and its structural characteristics were determined utilizing spectrum
techniques. The Pt(II) complexes have been investigated for their ability to combat
microorganisms and breast cancer. According to the findings of the investigation into
the complex's antibacterial action, Staphylococcus aureus, Escherichia coli, Candida
alblicans, and Aspergillus niger were all considerably impacted. Using the 2,2-
Diphenyl-1-picrylhydrazylradical scavenging activity assay (DPPH), it was examined
whether the Pt(II) complexes have antioxidant qualities and may be useful in the
treatment of disorders caused by free radicals. These novel complexes may be
exploited for these therapeutic purposes, according to this study's findings.
Keywords
Article Details
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References
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- characterization and biological Activity of β-Lactam and Thiazolidinone Derivatives
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- Beijing, China.
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- Identification of Organic Chemistry Compounds ", 6th Ed. , John Wiley and Sons , N.
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- Antibiotics. Front. Microbiol. 11: 1-12.
- Zearaha S. A., Al-Fartosy , A. J. M., and Al-Kanany G.F. (2013) Antibacterial
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- Shamkhy E.T., Ali V.S., Hassan H.F., Abd S.T., Al-Duboni G.I., Azeez R.A.
- (2017) Bioactivity of Formerly Synthesized Imino Phenol Ligand and its
- Organometallic Complexes. Biomed Pharmacol J. 10(1): 45-50.
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- Characterization, and Antioxidant, Antimicrobial and Toxic Properties of Novel Δ2-
- ,3,4-thiadiazoline and Δ2-1,3,4-selenadiazoline Derivatives. International Journal of
- Drug Delivery Technology. 12(1):113-126.
- Al-Fregi, A.A; Al-Salami, B. K.; Al-Khazragie, Z. K.; (2018) Synthesis,
- Characterization, Antimicrobialactivity and Antioxidant of Azo Schiff Bases
- Containing Sulfanilamide. J. Global Pharma Tech. 10, 952–962.
- Thi-Qar Medical Journal (TQMJ):Vol.( 26),No.(2),2023
- Web Site: https://jmed.utq.edu Email: utjmed@utq.edu.iq
- ISSN (Print):1992-9218
- Ivanova S., Balkanski S., Atanasov P., Chaneva M., Obreshkova D., Dimitrov
- V., Kazalukova K., Peikova L., Markov O. (2023) Antitumor and antioxidant activity
- of some metal complex compounds. Pharmacia. 70(2): 375–382.
- Al-Khazragie, Z. K., Al-Fartosy, A. J. M., & Al-Salami, B. K. (2022).
- Biochemical study of Some New Cephems and Selenacephems Based on 6H-1,3-
- Thiazines and 6H-1,3-selenazines. Biomedicine and Chemical Sciences, 1(2), 93–109.
- Al-Fartosy, A. J. M. (2011) Antioxidant properties of methanolic extract from
- Inula graveolens L., Turkish Journal of Agriculture and Forestry, 35(6): 591-596.
- Al-Fartosy, A. J. M. (2015) Protective effect of galactomannan extracted from
- Iraqi Lycium Barbarum L. fruits against alloxan-induced diabetes in rats. American
- Journal of Biochemistry & Biotechnology 11 (2), 74–83.
- Al-Fartosy, A. J. M., Abdulrazzaq, A. A. (2015) Antioxidant Activity of
- Anthocyanins Extracted from Iraqi Iresine herbstii L. Flowers after Drying and
- Freezing American American Journal of Analytical Chemistry, 6: 382-394.
- Al-Fartosy, A. J. M., & Al-Rikaby, A. K. J. (2007). The Antioxidative Action of
- Monoterpene From Loranthus europaeus L.seeds. Basrah Journal of Agricultural
- Sciences, 20(1), 322–336
References
Feng, W. et al (2017) Isolation and structure identification of flavonoids, Chapter
Science Press, Beijing, China.DOI: 10.5772/67810.
El-bendary, M.M.; Saleh, T.S.; Alomari, M.M.; Ali, E.M.M.; Davaasuren, B.;
Jaremko, M.; Babgi, B.A. (2022) Potential Anticancer Activities and Catalytic
Oxidation Efficiency of Platinum(IV) Complex. Molecules 27 (14): 1-19.
Al-Khazragie Z.K., Al-Salami B.K., Al-Fartosy A.J.M. (2022) Synthesis,
Antimicrobial, Antioxidant, Toxicity and Anticancer Activity of a New Azetidinone,
Thiazolidinone and Selenazolidinone Derivatives Based on Sulfonamide. Indonesian
Journal of Chemistry, 22(4): 979-1001.
Al-Khazragie Z.K., Al-Fartosy A.J.M., Al-Salami B.K. (2022) Synthesis,
characterization and biological Activity of β-Lactam and Thiazolidinone Derivatives
Based on Sulfonamide. Egypt. J. Chem. 65(6): 621-645.
Altun Z., Yoruç, Z., Boz, M. Synthesis and Biological activity of a New Pt(II)
Complex Involving 4-bromo-2,6-bis-hydroxymethyl-phenol and Nicotinamide (2021)
Iran. J. Chem. Chem. Eng. 41(10): 3233-3250.
B. Sanjib, P. Angelene, M. PiyaliR. B. S. Kumar and K.H. (2011)
Pallab,pharmaceutical biology, 49(9),927-935.
Al-Fregi, A. A.; Al-Salami, B. K.; Al-Khazragie, Z. K.; Al-Rubaie, A. Z.
Synthesis, Characterization and Antibacterial Studies of Some New Tellurated Azo
Compounds (2019) Phosphorus Sulfur Silicon Relat. Elem. 194, 33–38. DOI:
1080/ 10426507.2018.1470179.
Kedare, S.B. and Singh, R.P. (2011) Genesis and Development of DPPH Method
of Antioxidant Assay .J. Foodsci. Technol. 48,412.
Thi-Qar Medical Journal (TQMJ):Vol.( 26),No.(2),2023
Web Site: https://jmed.utq.edu Email: utjmed@utq.edu.iq
ISSN (Print):1992-9218
Al-Fregi, Adil. A.; Al-Rubaie, A. Z.; Al-Jadaan, S. A. S. (2010) Synthesis of a
new series of 2-(2-hydroxy naphthylazo)aryltellurium Compounds. Phosphorus Sulfur
Silicon Relat. Elem. 186, 115–124. DOI: 10.1080/10426507.2010.485154.
Liu,P.C. Liu,R. Liu and X.Wu, (2015) Medical science monitor basic research,21
,15-20.
Markham, K. R, (2017) Techniques of flavonoid identification. Science Press,
Beijing, China.
Nakamoto, K. (2009) "Infrared and Raman Spectra of Organic and Coordination
Compounds " , John Wiley and Sons Ltd. , USA , 7th Ed.
Shriner, R. I.; and. Hermann, C. K. (2004) " Spectroscopic Techniques for
Organic Chemistry ", John Wiley and Sons , N. Y.
Martin, G. E, (2002) " Cryogenic NMR Probs: Application, D. M. Grant and R.
K. Harris, " Encyclopedia of Nuclear Magnetic Resonance, Vol.9, Wiley Chichester.
Silerstien, R. M.; Webster. F. X.; Kiemle, D. J. (2005) "Spectrometric
Identification of Organic Chemistry Compounds ", 6th Ed. , John Wiley and Sons , N.
Y.
Ranpariya B, Salunke G, Karmakar S, Babiya K, Sutar S, Kadoo N, Kumbhakar
P and Ghosh S. (2021) Antimicrobial Synergy of Silver-Platinum Nanohybrids With
Antibiotics. Front. Microbiol. 11: 1-12.
Zearaha S. A., Al-Fartosy , A. J. M., and Al-Kanany G.F. (2013) Antibacterial
activity of the glycosidic extract from Citrus laurantifoia L.fruits. Der Pharma
Chemica, 5(6):73-78.
Shamkhy E.T., Ali V.S., Hassan H.F., Abd S.T., Al-Duboni G.I., Azeez R.A.
(2017) Bioactivity of Formerly Synthesized Imino Phenol Ligand and its
Organometallic Complexes. Biomed Pharmacol J. 10(1): 45-50.
Al-Khazragie ZK, Al-Salami BK, Al-Fartosy AJM. (2022) Synthesis,
Characterization, and Antioxidant, Antimicrobial and Toxic Properties of Novel Δ2-
,3,4-thiadiazoline and Δ2-1,3,4-selenadiazoline Derivatives. International Journal of
Drug Delivery Technology. 12(1):113-126.
Al-Fregi, A.A; Al-Salami, B. K.; Al-Khazragie, Z. K.; (2018) Synthesis,
Characterization, Antimicrobialactivity and Antioxidant of Azo Schiff Bases
Containing Sulfanilamide. J. Global Pharma Tech. 10, 952–962.
Thi-Qar Medical Journal (TQMJ):Vol.( 26),No.(2),2023
Web Site: https://jmed.utq.edu Email: utjmed@utq.edu.iq
ISSN (Print):1992-9218
Ivanova S., Balkanski S., Atanasov P., Chaneva M., Obreshkova D., Dimitrov
V., Kazalukova K., Peikova L., Markov O. (2023) Antitumor and antioxidant activity
of some metal complex compounds. Pharmacia. 70(2): 375–382.
Al-Khazragie, Z. K., Al-Fartosy, A. J. M., & Al-Salami, B. K. (2022).
Biochemical study of Some New Cephems and Selenacephems Based on 6H-1,3-
Thiazines and 6H-1,3-selenazines. Biomedicine and Chemical Sciences, 1(2), 93–109.
Al-Fartosy, A. J. M. (2011) Antioxidant properties of methanolic extract from
Inula graveolens L., Turkish Journal of Agriculture and Forestry, 35(6): 591-596.
Al-Fartosy, A. J. M. (2015) Protective effect of galactomannan extracted from
Iraqi Lycium Barbarum L. fruits against alloxan-induced diabetes in rats. American
Journal of Biochemistry & Biotechnology 11 (2), 74–83.
Al-Fartosy, A. J. M., Abdulrazzaq, A. A. (2015) Antioxidant Activity of
Anthocyanins Extracted from Iraqi Iresine herbstii L. Flowers after Drying and
Freezing American American Journal of Analytical Chemistry, 6: 382-394.
Al-Fartosy, A. J. M., & Al-Rikaby, A. K. J. (2007). The Antioxidative Action of
Monoterpene From Loranthus europaeus L.seeds. Basrah Journal of Agricultural
Sciences, 20(1), 322–336
