Assessement of interleukin 37 and some immune parameters in patients with giardiasis : A Case Control Study
DOI:
https://doi.org/10.32792/jmed.2025.29.27Keywords:
Giardia lamblia, Giardiasis, Diarrhea, interleukin 37Abstract
Background: Giardia lamblia is the cause of giardiasis, one of the most prevalentparasitic illnesses in the world that affects millions of people annually. Although
the majority of infections are most likely asymptomatic, some are linked to
intestinal irritation and subacute or chronic diarrhea, which can lead to
malabsorption and nutritional deficiencies, particularly in children.Aim of study
:is to Assessment of interleukin 37 and some immune parameters in patients with
giardiasis .Patients and methods:The stool samples were collected and labeled
with the patient's information in sterile plastic containers and checked via the
naked eye for colour, consistency, after that, they were analyzed using light
microscopy to check for the presence of Giardia trophozoite and cyst
stage.(45)blood samples were taken from suspected G. lamblia patients, and (45)
blood samples from healthy individuals as a control group. Blood samples were
captured to enable to establish the white blood cell (WBC) count. Results: The
outcomes of the research demonstrated that both male and female patients
infected with G. lamblia had significantly lower levels of IL-37 (p >0.05) in their
72.36 ±10.87 concentrations than in the control group (86.51 ±11.83). WBC
levels It reveals a substantial rise in the number of infected patients (8.94 ± 4.36)
in contrast to 7.44 ± 2.4 of the control collective. (P<0.05) . Conclusion : the
spread of the disease depends on the environmental conditions as well as on
factors specific to the host and the strength of occurrence affected by these
conditions.
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