ANTIPROTOSCOLICES ACTIVITY OF NONADECOIC ACID ; PHTHALIC ACID, DIFLOROPHENYL UNDECYL STER AND 1,2- BENZENDICARBOXYLIC ACID , BIS (2-ETHYLHEXYL ) ESTER EXTRACTED FROM CLADOPHORA CRISPATA AND HAPALOSIHON AUREUS COMPARED WITH ALBENDAZOLE
Abstract
The present study has aimed the hydatid disease , which is endemic in Iraq especially in Basrah city . Fatty acids compound (Nonadecoic acid ; Phthalic acid, diflorophenyl undecyl ster and 1,2- Benzendicarboxylic acid , bis (2-ethylhexyl ) ester ) extracted from Cladophora crispata and Hapalosihon have used and compared with albendazole . The results of the present study have found that compounds have activity against the protoscolices of hydatid cyst similar to the activity of albendazole and in low concentration .References
- Morar , R. and Feldman , C. (2003). Pulmonary echinococcosis . Eur. Respir. J. , 21 : 1069 – 1077.
- Lewis JW, Koss N, Kerstein MD(1995). A review of echinococcal disease. Ann Surg 1995; 18(4):390-396.
- Lorena V. Leَn-Deniz1, Eric Dumonteil2, Rosa Moo-Puc1,3, and Yolanda Freile-Pelegrin1.(2009). Antitrypanosomal in vitro activity of tropical marine algae extracts . Pharmaceutical Biology,; 47(9): 864–871.
- Schaeffer, D.J.; Krylov, V.S.(2000) Anti-HIV activity of extracts and compounds from algae and cyanobacteria. Ecotoxicol. Environ. Saf., 45, 208–227.
- Smit AJ (2004). Medicinal and pharmaceutical uses of seaweed natural products: A review. J. Appl. Phycol. 16: 245-262.
- Goud, J.P.; Se Shikala, D. and Singara Charya, M.A. (2007). Antibacterial activity and bimolecular composition of certain fresh water microalgae from river Godovari (India). Sci. Wor. J., 2 3: 19 – 23.
- Smyth, J. D. (1964). The biology of hydatid organisms. Adv. Parasitol. , 2: 169-219.
- Al-Eryani MAY (2002). Comparative study on the efficiency on Ivermectin drug and Peganum harmala seed extract on protoscoleces hydatid cyst. MSc Thesis, Al-Mustansiriya University,Baghdad.
- Barzinji AKR, Mothana RA, Nasher AK (2009). Effect of leaf extracts of Dendrosicyos socotrana and Jatropha unicostata on the viability of Echinococcus granulosus protoscoleces. EurAsia J BioSci 3, 16, 122-129.
- Kern, P., 2003. Echinococcus granulosus infection: clinical presentation, medical treatment and outcome. Langenbeck,s Archives of Surgery, 388: 413-20.
- Rodrigues, E., S. Tilvi and C.G. Naik, 2004. Antimicrobial activity of marine organisms collected off the coast of East India. J. Exp. Biol. Ecol., 309: 121-127.
-Tuney, I., B.H. Cadirci, D. Nal and A. Sukatar, 2006. Antimicrobial activities of the extracts of marine algae from the coast of Urla (Izmir, Turkey). Turk. J. Biol., 30: 171-175.
- Al- Nasir, (2010) .Isolation and Identification of some active compounds from the green alga Cladophora crispata with their bioactivity test .M.Sc.thesis.college of education , university of Basrah.
- CHABALGOITY,1A* JULIA A. HARRISON,1 ADRIANA ESTEVES,2 RAQUEL DEMARCO DE HORMAECHE,1 RICARDO EHRLICH,2C. M. ANJAM KHAN,1 AND CARLOS E. HORMAECHE1(1997). Expression and Immunogenicity of an Echinococcus granulosusFatty Acid-Binding Protein in Live Attenuated Salmonella Vaccine Strains . INFECTION AND IMMUNITY, p. 2402–2412 .
- Jakobsson , E. (2005). Structural studies of Echinococcus granulosus fatty acid binding protein 1 and human semicarbazide – sensitive amine oxidase . Ph.D. thesis . Uppsala university , Sweden . pp : 65 .
- Storch , J. and Thumser , A. E. (2000). The fatty acid transport function of the fatty acids binding proteins . Biochem. Biophys. Acta. 36: 28- 44
- Zimmerman and Veerkamp , 2002 ;
- Haunerland , N.H. and Spencer , F. (2004). Fatty acids binding proteins – insight genetic manipulation . Prog. Lipid Res. 43 :328- 349.
- Galbraith, H. and Miller, T. B. (1973). Physiochemical effects of long chain fatty acids and bacterial cells, and their protoplast. J. Appl. Bact., 36: 647 – 658.